Browse all practice questions for the NAPLEX Contraception and Infertility Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • How is breakthrough bleeding on combined oral contraceptives typically managed?
  • Which infertility medication acts as a selective estrogen receptor modulator and induces ovulation, with estrogen agonist activity in some tissues and antagonist in others?
  • Which drug is known to cause an LH surge when used for ovulation induction?
  • How many patch contraindications are listed in the material?
  • When should progestin-only pills be started?
  • Which contraception approach is considered acceptable for patients with hypertension?
  • Which contraception method has the fewest systemic estrogen-related contraindications?
  • Which reversible contraceptive method is associated with a delay in return to fertility after stopping?
  • DMPA routes include IM or SC. Which option correctly states this?
  • What OC is approved for suppressing menses altogether with continuous contraception?
  • Which of the following is an iron-containing monophasic COC example?
  • Which tests assess tubal patency and uterine anatomy during infertility workup?
  • For estrogen-containing patch, which factor is a contraindication due to an increased risk of thromboembolism?
  • In PCOS, which ovulation induction agent has shown superior live birth rates in some trials?
  • Which of the following statements about extended-cycle COC bleeding patterns is true?
  • Which of the following is NOT listed as a contraindication to estrogen use?
  • How long is the NuvaRing worn before removal?
  • How long does fertility typically take to return after stopping DMPA?
  • What is the dose and timing for Plan B levonorgestrel emergency contraception?
  • Which component is estrogen in COCs?
  • Which progestin is listed as having lower androgenic activity and used to address acne or hirsutism?
  • What is a documented concern with long-term use of DMPA injections?
  • Which group should avoid using estrogen-containing pills, rings, or patches due to a risk of serious cardiovascular events?
  • Which contraception methods require clinician insertion?
  • Sunday-start COC requires how many days of backup?
  • In labeling, 'lo' estrogen content means the pill has at most how many mcg of estrogen?
  • Which metabolic feature is commonly associated with PCOS and may contribute to infertility?
  • Which contraception methods are known for long-term cost-effectiveness?
  • Which statement about transdermal estrogen-containing patches is true?
  • Which contraception methods require a clinician for insertion?
  • Which of the following is an indication for COC use?
  • What is the recommended postpartum contraception option (DOC)?
  • Which of the following is not listed among the monophasic COC formulations in the material?
  • Which statement best describes a copper intrauterine device?
  • For contraception counseling, what factors should be considered?
  • For a progestin-only pill, if a dose is missed by more than 3 hours, what should you do?
  • Which medication is NOT listed as reducing the effectiveness of estrogen-containing contraceptives?
  • Nexplanon releases which progestin, and for how long?
  • Which scenario is most appropriate for performing intrauterine insemination?
  • Which medications can reduce the effectiveness of estrogen-containing contraceptives?
  • Which statement best describes a contraindication to estrogen-containing contraception?
  • Which of the following statements about Nonoxynol-9 is true?
  • What is the purpose of the GnRH antagonist in IVF protocols?
  • Which option is listed as a treatment for heavy menstrual bleeding (menorrhagia)?
  • For breastfeeding patients, which contraception option is documented?
  • Which medication is used to treat miscarriage?
  • Which of the following is listed as a patch contraindication?
  • What is the dosing schedule for depot medroxyprogesterone acetate (DMPA) contraception?
  • Clomiphene citrate is associated with which adverse outcome?
  • The oocyte lives for ___ hours once released
  • What non-contraceptive benefit is associated with LNG IUS?
  • For breakthrough bleeding with less than 30 mcg estrogen, what adjustment is recommended?
  • If the vaginal ring is kept in place for 4 weeks, what is recommended before inserting a new ring?
  • Before dispensing, what storage guidance is given for the vaginal ring?
  • What is the mechanism of action of ulipristal acetate as emergency contraception?
  • Which combined oral contraceptive is designed for an extended-cycle regimen?
  • Which test assesses male factor fertility in infertility evaluation?
  • What is the main difference in hormone exposure between copper IUD and LNG IUS?
  • When is the best time to have sex if you want a baby?
  • Hormonal contraceptives MOA
  • Which of the following is a progestin-only pill formulation?
  • In infertility management, intrauterine insemination is typically used to deliver sperm when?
  • Which statement best describes the 'freeze-all' approach?
  • Which contraceptive patch is exemplified in the material?
  • What does the start of menses indicate?
  • Monophasic meaning
  • Preconception health includes avoiding hazardous drugs.
  • What is the purpose of using a GnRH agonist trigger in antagonist protocol?
  • Which regimen is described as a mood-change option among contraception choices?
  • When should hCG be tested for pregnancy?
  • If later in the cycle breakthrough bleeding occurs, what adjustment should be considered?
  • Multiphasic formulations include which of the following?
  • Preconception health includes staying up to date on vaccinations.
  • Which ovarian stimulation protocol is recommended to reduce the risk of ovarian hyperstimulation syndrome (OHSS)?
  • Which contraception options are generally considered safe for cancer survivors, depending on cancer type?
  • What is the primary purpose of folic acid supplementation in pregnancy?
  • Nexplanon is a long-acting reversible contraception implanted under the skin.
  • Which method is a COMBINED (estrogen and progestin) contraception option?
  • Which delivery methods are available for estrogen/progestin combination contraception?
  • Which symptom is part of the ACHES acronym used to recognize rare estrogen-related adverse events?
  • Which of the following describes the typical initial steps in an infertility evaluation?
  • Drospirenone-containing formulations are associated with which diuretic effect?
  • What semen analysis parameter defines azoospermia?
  • Which estrogen-containing contraception is contraindicated in migraine with aura?
  • Which type of lubricant is recommended with condoms?
  • Nonoxynol-9 is what type of agent?
  • Which herbal supplement is known to interact with hormonal contraceptives?
  • How long can a vaginal ring be stored at room temperature before use?
  • Preconception health includes asking your MD to evaluate whether any medications you are taking are teratogenic.
  • In infertility guidelines, a shorter evaluation time is recommended for women aged 35 or older. What is that time frame?
  • Which of the following is a PROGESTIN-ONLY contraception option?
  • Which laboratory markers assess ovarian reserve commonly used in infertility evaluation?
  • Which statement about diaphragm usage is true?
  • The risk of clotting increases with higher estrogen exposure.
  • Letrozole belongs to which class of ovulation induction agents?
  • During the luteal phase, which hormone is dominant?
  • Ulipristal acetate (Ella) emergency contraception can be used up to how many days after unprotected sex?
  • Which contraception method is associated with heavier menstrual bleeding and cramps?
  • When is a copper IUD preferred over LNG IUS?
  • If early or midcycle spotting occurs, what adjustment is recommended?
  • Patch effectiveness decreases in women weighing more than which weight threshold?
  • Why would someone use progestin-only pills?
  • For breakthrough bleeding with 30 mcg or more estrogen, what adjustment is recommended?
  • What is the mechanism of action of the etonogestrel implant?
  • After a missed period while using contraception, when should you consider a pregnancy test?
  • A patient with a history of DVT/PE should avoid which type of contraception?
  • Which therapy is used when poor response to clomiphene or letrozole or to spur egg release for procedures?
  • Which is considered a first-line pharmacologic treatment for PMDD?
  • IUD is a device placed inside the uterus.
  • Which method is a hormonal long-acting reversible contraception?
  • What are the diagnostic criteria for PCOS?
  • What contraception is recommended postpartum for breastfeeding mothers?
  • Which of the following is a common adverse effect of clomiphene citrate?
  • Which of the following is true about vaginal sponge counseling?
  • In male-factor infertility, which technique can bypass many sperm defects?
  • What is the primary adverse effect of Plan B and how is it managed if emesis occurs within 2 hours?
  • What is unique about drospirenone among COCs?
  • What monitoring is recommended after initiating combined hormonal contraception?
  • What is the main difference between perfect-use and typical-use rates?
  • Where can the contraceptive patch be applied?
  • Infertility is defined as failure to conceive after at least how long of unprotected intercourse?
  • Which of the following is NOT an indication for combined oral contraceptives?
  • Which anticonvulsant is a known enzyme inducer that can reduce hormonal contraceptive effectiveness?
  • Which ultrasound finding supports the diagnosis of PCOS?
  • Which emergency contraception option is non-hormonal and can provide long-term contraception?
  • If starting COC on the first day of the period (first-day-start) and you begin within 5 days of onset, what backup is required?
  • Which contraception option has the lowest failure rate and is not user-dependent?
  • How is ovulation typically confirmed in infertility assessment?
  • What is the typical-use failure rate for male condoms?
  • In terms of estrogen exposure, how do transdermal patches compare with combined oral contraceptives?
  • Contraceptive foams, films, creams, etc contain which spermicide?
  • Which of the following is an example of a combined estrogen-progestin contraception method?
  • Compared with combined oral contraceptives, estrogen exposure from vaginal rings is typically:
  • Which medication requires backup contraception for 6 weeks after stopping due to interaction with hormonal contraceptives?
  • What is the daily folic acid dose during pregnancy?
  • Which of the following options is considered a nonhormonal contraception?
  • What is the daily folic acid dose for nonpregnant adults?
  • Which of the following is a nonhormonal contraception option?
  • Which are common adverse effects of combined oral contraceptives?
  • Which of the following is NOT a monophasic COC formulation?
  • Errin is an example of which type of contraception?
  • Which contraceptive method is permanent?
  • For patients with migraine with aura, which contraception should be avoided?
  • Which of the following is a progestin used in combined oral contraceptives?
  • What are the 3 phases of the menstrual cycle?
  • Among emergency contraception options, which is described as the most effective and lasts up to 10 years?
  • After initiating combined hormonal contraception, patients should be counseled to monitor for which warning signs?
  • Which of the following is an indication for COC use?
  • Tracking which type of body temperature is used to predict ovulation?
  • What surge triggers ovulation?
  • If a combined OC pill is missed during the third week, what is the recommended action?
  • Mavyret should be avoided with any estrogen-containing contraception containing more than 20 mcg ethinyl estradiol due to risk of what?
  • What is counted as day 1 of the cycle?
  • Which of the following is a daily folic acid dose for nonpregnant adults?
  • Preconception health for wanting to have a baby includes increasing folic acid.
  • Preconception health for wanting to have a baby includes stopping smoking, drinking, and using drugs.
  • What is the mechanism of Letrozole in ovulation induction?
  • What is the typical length of a normal menstrual cycle?
  • How is infertility defined in most guidelines?
  • What do ovulation kits test for?
  • Which HIV protease inhibitor is known to interact with hormonal contraception?
  • Which of the following is not typically associated with PCOS infertility?
  • Which contraceptive option should be avoided if weight gain is a concern?
  • Which estrogen-related adverse effect is specifically linked to fluid retention?
  • Which health benefit is associated with hormonal contraceptives?
  • Which statement correctly identifies the components of combined oral contraceptives (COCs)?
  • Typically, how many days of backup contraception are recommended after starting combined oral contraception, unless using the first-day-start method?
  • Which medication is a prostaglandin analog used to treat miscarriage?
  • What is unique about drospirenone in some COCs?
  • Which medication is a prostaglandin analog used to treat miscarriage?
  • For foams, creams, jellies, and suppositories, which usage is correct?
  • DMPA is administered IM or SC every ___ months?
  • What is the duration of effectiveness for the LNG-releasing intrauterine system?
  • What is the difference between IVF and IUI?
  • Which option is acceptable for migraine without aura regarding contraception selection?
  • What characterizes a patient-centered counseling approach in contraception?
  • For a patient who is 36 years old, after how many months of regular unprotected intercourse without conception is infertility diagnosed according to most guidelines?
  • How are gonadotropins administered?
  • When is intrauterine insemination indicated in infertility treatment?
  • Extended cycle COC involve ___ days of active hormonal pills followed by 7 days of inactive.
  • Which progestin with no androgenic activity is listed as an option for acne or hirsutism?
  • Progestin-only pills must be taken within how many hours of the scheduled time?
  • What is the only method 100% effective in preventing both pregnancy and sexually transmitted infections?
  • In PCOS, which features are commonly seen in infertility?
  • Which statement best describes multiphasic COC formulations (biphasic, triphasic, quadraphasic)?
  • Miscarriage is defined as a nonviable pregnancy up to how many weeks of gestation?
  • Which infertility treatment is associated with an increased risk of multiple births due to release of multiple eggs?
  • What is the duration of a patch cycle before a patch-free week?
  • Which fertility treatment carries the highest risk of ovarian hyperstimulation syndrome (OHSS)?
  • Which regimen is suggested for patients with mood changes or disorders?
  • To reduce nausea associated with oral contraceptives, which of the following is recommended?
  • What document is required by the FDA to be dispensed with oral contraceptives?
  • Which progestin is contained in the Mirena intrauterine device?
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